Optometry and Vision Science: Recent submissions
Now showing items 1-20 of 247
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The Effect of Freezing on the Elution of PVA from Contact Lenses
(University of Waterloo, 2024-04-30)Contact lenses are widely used, with over 140 million wearers globally. Wearing contact lenses can cause symptoms of discomfort and dryness, which affect nearly half of all wearers. To address this concern, this thesis ... -
Exploration of the Underlying Visual Perceptual and Cognitive Mechanisms of Dynamic Visual Acuity
(University of Waterloo, 2024-01-25)Purpose: Dynamic visual acuity (dynamic VA) is a complex, perceptual ability of the visual system that involves determining fine details of objects as they move across one’s field of view (1–4). Over the years, there has ... -
Investigating the enhancement of visual cortex plasticity through non-invasive brain stimulation
(University of Waterloo, 2024-01-02)Purpose: (1) To investigate the effects of various non-invasive brain stimulation (NIBS) modalities, including high-frequency transcranial random noise stimulation (hf-tRNS), anodal transcranial direct current stimulation ... -
Fabrication of microfluidic chip using 3D printing for ocular cell studies
(University of Waterloo, 2023-09-25)Purpose: This thesis aimed to create a polydimethylsiloxane (PDMS) microfluidic chip utilizing low-cost commercial 3D printers and to integrate human corneal epithelial cells (HCEC) into the fabricated chip. Methods: The ... -
Advancing Hyperacuity for Vision Screening
(University of Waterloo, 2023-09-22)Introduction: The human visual system is extremely sensitive to certain spatial visual tasks. It can detect the subtle misalignment of closer objects to a degree of 2-5 arcseconds, which is smaller than the foveal cone ... -
Optometry Outreach in Indigenous Communities in British Columbia, Saskatchewan, and Manitoba
(University of Waterloo, 2023-08-31)Introduction: Inuit, Métis, and First Nations, the three main Indigenous groups within Canada, face disproportionate barriers to access for primary eye and vision care. Optometrists visit rural and remote Indigenous ... -
The Phenotype of Tear Neutrophils and Their Role in Ocular Homeostasis and Inflammation
(University of Waterloo, 2023-07-31)Introduction: Neutrophils (polymorphonuclear neutrophils, PMNs) are part of the innate immune system with potent killing mechanisms against pathogens. Although the anterior segment of the eye has a unique characteristic, ... -
Fabrication of an enzyme responsive biomaterial for the treatment of recurrent corneal erosion
(University of Waterloo, 2023-04-11)Purpose: Recurrent corneal erosion (RCE) arising from the loss of superficial corneal epithelial cells causes tremendous ocular pain affecting one’s productivity and quality of life. RCE was traditionally treated with eye ... -
Understanding concussion in para athletes with vision impairment
(University of Waterloo, 2023-02-15)Sports-related concussions occur in para sport as they do in able-bodied sport. There is evidence to suggest athletes with vision impairment (VI) may be more likely to sustain concussion injuries compared to athletes with ... -
Diabetic retinopathy grading with respect to the segmented lesions
(University of Waterloo, 2022-05-19)One of the leading causes of irreversible vision loss is Diabetic Retinopathy (DR). The International Clinical Diabetic Retinopathy scale (ICDRS) provides grading criteria for DR. Deep Convolutional Neural Networks (DCNNs) ... -
Effects of ML-7 on the Actomyosin Networks of the Avian Crystalline Lens
(University of Waterloo, 2022-04-29)Assemblies of contractile proteins such as actin, myosin and myosin light chain kinase (MLCK) are found on the posterior surface of the lens fibre cells. The mechanical properties of chicken lenses, as well as their focal ... -
A differential role for the posterior cerebellum in the adaptive control of convergence eye movements
(Elsevier, 2020-02)Introduction The vergence oculomotor system possesses two robust adaptive mechanisms; a fast “dynamic” and a slow “tonic” system that are both vital for single, clear and comfortable binocular vision. The neural substrates ... -
Impact of contact lens wear on epithelial alterations in keratoconus
(Elsevier, 2021-03)Purpose The purpose of this study was to characterize the central epithelial thickness (CET) of penetrating keratoplasty corneal specimens obtained from patients with keratoconus (KC) and correlate the histological patterns ... -
The Optometric Management of Concussion
(University of Waterloo, 2022-01-31)Traumatic brain injury is a major public health problem that affects millions of people annually and hundreds of people experience brain injury daily. Many of these individuals develop visual symptoms. Optometrists play a ... -
A System for Ocular Surface Temperature Measurement Using Infrared Thermography
(University of Waterloo, 2022-01-20)Background: Ocular surface temperature (OST) is affected by changes in the physiology of the eye caused by normal homeostasis, environmental changes, or systemic and local disease. OST can help a physician to diagnose eye ... -
Examination of Contact Lenses and Dry Eye Using Evaporimetry
(University of Waterloo, 2022-01-14)Purpose: Evaporimetry is a non-invasive technique used to assess the stability of the tear film. The test measures the rate of tear evaporation, and has been used to investigate dry eye, contact lenses, and the efficacy ... -
Uptake and release of preservatives from soft contact lens materials
(University of Waterloo, 2022-01-13)Purpose: The purpose of this thesis was to examine the uptake and release of myristamidopropyl dimethylamine (MAPD) and polyhexamethylene biguanide (PHMB) from soft contact lens material using various in vitro models to ... -
Attentional Factors Underlying Binocular Vision Loss in Amblyopia
(University of Waterloo, 2022-01-13)Amblyopia is a neurodevelopmental disorder of vision that results from abnormal visual experience during early development. In addition to significant vision loss in one eye, individuals with amblyopia experience binocular ... -
Stimulus characteristics of a novel air-based multiple stimulus aesthesiometer
(University of Waterloo, 2022-01-05)Purpose: To (1) develop a novel air-based aesthesiometer capable of producing and applying multiple stimuli separated either by time or space; (2) identify the stimulus airflow characteristics and confirm the consistency ... -
Ocular Surface Sensory Processing and Signal Detection Theory
(University of Waterloo, 2021-09-28)Purpose: The main aim of the experiments in this thesis is to evaluate the feasibility of using signal detection theory (SDT) to determine the detectability and bias of various ocular surface pneumatic stimuli. Chapter ...