Browsing University of Waterloo by Author "Fuzzen, Meghan"
Now showing items 1-11 of 11
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An Assessment of the Spatial and Temporal Variability of Biological Responses to Municipal Wastewater Effluent in Rainbow Darter (Etheostoma caeruleum) Collected along an Urban Gradient
Fuzzen, Meghan; Bragg, Leslie M.; Tetreault, Gerald R.; Bahamonde, Paulina; Tanna, Rajiv N.; Bennett, Charles J.; McMaster, Mark E.; Servos, Mark R. (PLOS, 2016-10-24)Municipal wastewater effluent (MWWE) and its constituents, such as chemicals of emerging concern, pose a potential threat to the sustainability of fish populations by disrupting key endocrine functions in aquatic organisms. ... -
Biological responses in fish exposed to municipal wastewater treatment plant effluent in situ
Tetreault, G .R.; Kleywegt, S.; Marjan, P.; Bragg, L.; Arlos, M.; Fuzzen, Meghan; Smith, B.; Moon, T.; Massarsky, A.; Metcalfe, C.; Oakes, K.; McMaster, M. E.; Servos, Mark. R. (IWA Publishing, 2021-04-16)Effluents from municipal wastewater treatment plants (MWTPs) are complex mixtures of chemicals including endocrine-disrupting compounds (EDCs) and 17α-ethynylestradiol (EE2). The objective of this study was to evaluate ... -
Community Surveillance of Omicron in Ontario: Wastewater-based Epidemiology Comes of Age
Arts, Eric; Brown, Stephen; Bulir, David; Charles, Trevor C.; DeGroot, Christopher T.; Delatolla, Robert; Desaulniers, Jean-Paul; Edwards, Elizabeth A.; Fuzzen, Meghan; Gilbride, Kimberly; Gilchrist, Jodi; Goodridge, Lawrence; Graber, Tyson E.; Habash, Marc; Jüni, Peter; Kirkwood, Andrea; Knockleby, James; Kyle, Christopher; Landgraff, Chrystal; Mangat, Chand; Manuel, Douglas G.; McKay, R. Michael; Mejia, Edgard; Mloszewska, Aleksandra; Ormeci, Banu; Oswald, Claire; Payne, Sarah Jane; Peng, Hui; Peterson, Shelley; Poon, Art F. Y.; Servos, Mark. R.; Simmons, Denina; Sun, Jianxian; Yang, Minqing; Ybazeta, Gustavo (Research Square, 2022-03-15)Wastewater-based surveillance of SARS-CoV-2 RNA has been implemented at building, neighbourhood, and city levels throughout the world. Implementation strategies and analysis methods differ, but they all aim to provide rapid ... -
Does intersex matter? A case study of rainbow darter in the Grand River
Fuzzen, Meghan (University of Waterloo, 2016-12-21)Endocrine disrupting compounds (EDCs) are present in the environment and can have negative effects on the health of wildlife. Aquatic organisms residing near the outfalls of municipal wastewater effluent (MWWE) are chronically ... -
Emergence and Spread of the SARS-CoV-2 Omicron Variant in Alberta Communities Revealed by Wastewater Monitoring
Hubert, Casey R. J.; Acosta, Nicole; Waddell, Barbara J.; Hasing, Maria E.; Qiu, Yuanyuan; Fuzzen, Meghan; Harper, Nathanael B. J.; Bautista, María A.; Gao, Tiejun; Papparis, Chloe; Doorn, Jean V.; Du, Kristine; Xiang, Kevin; Chan, Leslie; Vivas, Laura; Pradhan, Puja; McCalder, Janine; Low, Kashtin; England, Whitney E.; Kuzma, Darina; Conly, John; Ryan, M. Cathryn; Achari, Gopal; Hu, Jia; Cabaj, Jason L.; Sikora, Chris; Svenson, Larry; Zelyas, Nathan; Servos, Mark. R.; Meddings, Jon; Hrudey, Steve E.; Frankowski, Kevin; Parkins, Michael D.; Pang, Xiaoli; Lee, Bonita E. (medRxiv, 2022-10-03)Wastewater monitoring of SARS-CoV-2 allows for early detection and monitoring of COVID-19 burden in communities and can track specific variants of concern. Targeted assays enabled relative proportions of SARS-CoV-2 Omicron ... -
Modeling the exposure of wild fish to endocrine active chemicals: Potential linkages of total estrogenicity to field-observed intersex
Arlos, Maricor J.; Parker, Wayne J.; Bicudo, José R.; Law, Pam; Hicks, Keegan A.; Fuzzen, Meghan; Andrews, Susan A.; Servos, Mark. R. (Elsevier, 2018-08-01)Decades of studies on endocrine disruption have suggested the need to manage the release of key estrogens from municipal wastewater treatment plants (WWTP). However, the proposed thresholds are below the detection limits ... -
Multiplex RT-qPCR assay (N200) to detect and estimate prevalence of multiple SARS-CoV-2 Variants of Concern in wastewater
Fuzzen, Meghan; Harper, Nathanael B. J.; Dhiyebi, Hadi; Srikanthan, Nivetha; Hayat, Samina; Peterson, Shelley; Yang, Ivy; Sun, Jianxian; Edwards, Elizabeth A.; Giesy, John P.; Mangat, Chand S.; Graber, Tyson E.; Delatolla, Robert; Servos, Mark. R. (medRxiv, 2022-04-13)Wastewater-based surveillance (WBS) has become an effective tool around the globe for indirect monitoring of COVID-19 in communities. Quantities of viral fragments of SARS-CoV-2 in wastewater are related to numbers of ... -
Near real-time determination of B.1.1.7 in proportion to total SARS-CoV-2 viral load in wastewater using an allele-specific primer extension PCR strategy
Graber, Tyson E.; Mercier, Élisabeth; Bhatnagar, Kamya; Fuzzen, Meghan; D'Aoust, Patrick M.; Hoang, Huy-Dung; Tian, Xin; Towhid, Syeda Tasneem; Plaza-Diaz, Julio; Eid, Walaa; Alain, Tommy; Butler, Ainslie; Goodridge, Lawrence; Servos, Mark. R.; Delatolla, Robert (Elsevier, 2021-10-15)"The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome corona- virus 2 (SARS-CoV-2) has claimed millions of lives to date. Antigenic drift has resulted in viral variants ... -
Reduction of intersex in a wild fish population in response to major municipal wastewater treatment plant upgrades
Hicks, Keegan A.; Fuzzen, Meghan; McCann, Emily K.; Arlos, Maricor J.; Bragg, Leslie M.; Kleywegt, Sonya; Tetreault, Gerald R.; McMaster, Mark E.; Servos, Mark. R. (American Chemical Society, 2017)Intersex in fish downstream of municipal wastewater treatment plants (MWWTPs) is a global concern. Consistent high rates of intersex in male rainbow darter (Etheostoma caeruleum) have been reported for several years in the ... -
The Role of Wastewater Testing for SARS-CoV-2 Surveillance
Manuel, Douglas G.; Delatolla, Robert; Fisman, David; Fuzzen, Meghan; Graber, Tyson E.; Katz, Gabrielle M.; Kim, JinHee; Landgraff, Chrystal; MacKenzie, Alex; Maltsev, Antonina; Majury, Anna; McKay, R. Michael; Minnery, John; Servos, Mark. R.; Weese, J. Scott; McGeer, Allison; Born, Karen B.; Barrett, Kali; Schwartz, Brian; Jüni, Peter (Ontario COVID-19 Science Advisory Table, 2021-08-26)Wastewater testing for SARS-CoV-2 is relatively new; however, it builds on existing public health surveillance infrastructure. There is a limited but growing evidence base for its use, despite notable interpretation ... -
Wastewater to clinical case (WC) ratio of COVID-19 identifies insufficient clinical testing, onset of new variants of concern and population immunity in urban communities
D'Aoust, Patrick M.; Tian, Xin; Towhid, Syeda Tasneem; Xiao, Amy; Mercier, Elisabeth; Hegazy, Nada; Jia, Jian-Jun; Wan, Shen; Kabir, Md Pervez; Fang, Wanting; Fuzzen, Meghan; Hasing, Maria; Yang, Minqing Ivy; Sun, Jianxian; Plaza-Diaz, Julio; Zhang, Zhihao; Cowan, Aaron; Eid, Walaa; Stephenson, Sean; Servos, Mark. R.; Wade, Matthew J.; MacKenzie, Alex E.; Peng, Hui; Edwards, Elizabeth A.; Alm, Eric J.; Graber, Tyson E.; Delatolla, Robert (medRxiv, 2022-04-20)Clinical testing has been the cornerstone of public health monitoring and infection control efforts in communities throughout the COVID-19 pandemic. With the extant and anticipated reduction of clinical testing as the ...