Now showing items 1-4 of 4

    • DNA Adsorption by ZnO Nanoparticles near Its Solubility Limit: Implications for DNA Fluorescence Quenching and DNAzyme Activity Assays 

      Ma, Lingzi; Liu, Biwu; Huang, Po-Jung Jimmy; Zhang, Xu; Liu, Juewen (American Chemical Society, 2016-06-07)
      Zinc oxide (ZnO) is a highly important material, and Zn2+ is a key metal ion in biology. ZnO and Zn2+ interconvert via dissolution and hydrolysis/condensation. In this work, we explore their interactions with DNA, which ...
    • A DNAzyme requiring two different metal ions at two distinct sites 

      Zhou, Wenhu; Zhang, Yupei; Huang, Po-Jung Jimmy; Ding, Jinsong; Liu, Juewen (Oxford University Press, 2015-12-10)
      Most previously reported RNA-cleaving DNAzymes require only a single divalent metal ion for catalysis. We recently reported a general trivalent lanthanide-dependent DNAzyme named Ce13d. This work shows that Ce13d requires ...
    • A Selective Na+ Aptamer Dissected by Sensitized Tb3+ Luminescence 

      Zhou, Wenhu; Ding, Jinsong; Liu, Juewen (Wiley, 2016-08-17)
      A previous study of two RNA-cleaving DNAzymes, NaA43 and Ce13d, revealed the possibility of a common Na+ aptamer motif. Because Na+ binding to DNA is a fundamental biochemical problem, the interaction between Ce13d and Na+ ...
    • A Silver DNAzyme 

      Saran, Runjhun; Liu, Juewen (American Chemical Society, 2016-04-05)
      Silver is a very common heavy metal, and its detection is of significant analytical importance. DNAzymes are DNA-based catalysts; they typically recruit divalent and trivalent metal ions for catalysis. Herein, we report a ...

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