Browsing Theses by Title
Now showing items 10682-10701 of 15655
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Optimization of Mucoadhesive Polymer Micelles for Drug Delivery and Ophthalmic Formulations
(University of Waterloo, 2019-08-29)Nanotechnology enable medicine (nanomedicine) is expected to be the next advent of the health care market, facilitating efficient, safe, and personalized therapies. But there has been limited success penetrating the market. ... -
Optimization of Multiple Wells in Carbon Sequestration
(University of Waterloo, 2015-01-15)Injection of CO2 in saline aquifers is considered as one of the best strategies for the reduction of greenhouse gases. In order to select a potential saline aquifer storage site for carbon sequestration, many parameters ... -
Optimization of Neck Musculature Activation for Head Kinematics in Frontal, Lateral and Rear Impact Simulations
(University of Waterloo, 2020-07-21)The activation of the neck musculature plays an important role in the response of the head and neck and can affect the risk of injury under impact conditions. Yet, the role of the level (i.e., magnitude) and timing of the ... -
Optimization of Policy Evaluation and Policy Improvement Methods in Portfolio Optimization using Quasi-Monte Carlo Methods
(University of Waterloo, 2024-05-24)Machine learning involves many challenging integrals that can be estimated using numerical methods. One application of these methods which has been explored in recent work is the estimation of policy gradients for ... -
Optimization of Recombinant Protein Production by a Fungal Host
(University of Waterloo, 2007-04-05)The natural ability of filamentous fungi to synthesize, glycosylate, and secrete high levels of protein products has made them potentially attractive hosts for heterologous protein production. Advances in fungal genetics ... -
Optimization of Recombinant Protein Production by Streptomyces lividans Host
(University of Waterloo, 2010-05-26)Interleukin-3 is a cytokine, which acts on many target cells within the haemopoietic system, often in synergy with the other cytokines. Streptomyces lividans NCIMB 11416/IL3 p002 secreting human interleukin-3 was used as ... -
Optimization of Rooftop Delineation from Aerial Imagery with Deep Learning
(University of Waterloo, 2023-08-21)High-definition (HD) maps of building rooftops or footprints are important for urban application and disaster management. Rapid creation of such HD maps through rooftop delineation at the city scale using high-resolution ... -
Optimization of Solid Phase Microextraction for Determination of Disinfection By-products in Water
(University of Waterloo, 2012-04-17)A new technique for sample preparation and trace analysis of organic pollutants in water using mixed-phase thin film (MPTF) devices, combined with direct thermal desorption, cold trapping, gas chromatography-mass spectrometry ... -
Optimization of SPME coating characteristics for metabolomics and targeted analysis with LC/MS
(University of Waterloo, 2015-09-23)Metabolomics data provides complementary information to proteomics, genomics, and transcriptomics, in addition to enabling the tracking of the dynamic reactions in living systems. Metabolomics is widely used in various ... -
Optimization of Sweep Visually Evoked Potential (sVEP) in Adults
(University of Waterloo, 2008-05-01)Purpose and hypothesis: The purpose of this study was to optimize and standardize the following parameters of sweep Visually Evoked Potential (sVEP) in adults: criteria for fitting the regression line to estimate threshold, ... -
Optimization of the Migration of Virtual Machines Over a Bipartite Mesh Network Topology
(University of Waterloo, 2015-04-22)In today's society, the core network is becoming increasingly important to provide support for the ever growing number of end users as well as the applications that are required to run. While network technology continues ... -
Optimization of the Optical Infrastructure and Trapping Potential for a Quantum Processor Based on Trapped Barium Ions
(University of Waterloo, 2024-02-02)Trapped ion quantum computers represent a cutting-edge quantum computing platform, keeping the highest reported state preparation and measurement fidelity of 99.97%. Recently, barium ion has emerged as the research ... -
Optimization of the Use of Post-Industrial Recycled Multilayer Plastic Packaging (MPP) as Asphalt Modifier
(University of Waterloo, 2023-04-27)The quality of road infrastructure significantly impacts the safety and comfort of road users and the country's economy. In Canada, 15% of roads are rated poor or very poor, with 108,000 km in poor condition, costing drivers ... -
Optimization of Thermoelectric Chalcogenides
(University of Waterloo, 2015-01-23)Thermoelectric (TE) materials can convert heat into electricity when a temperature gradient is applied (Seebeck effect), and can pump heat from the cold end to the hot end using electricity (Peltier effect). These materials ... -
Optimization of Three-Axis Vertical Milling of Sculptured Surfaces
(University of Waterloo, 2010-05-12)A tool path generation method for sculptured surfaces defined by triangular meshes is presented in this thesis along with an algorithm that helps determine the best type of cutter geometry to machine a specific ... -
Optimization of Tin Selenide Thermoelectric Properties
(University of Waterloo, 2023-01-27)The high performance thermoelectric material tin selenide is of notable interest to the field of thermoelectric materials; since breaking the record for being the most efficient thermoelectric material due to the ultralow ... -
Optimization of Type-I Clathrates for Thermoelectric Properties
(University of Waterloo, 2012-10-04)The increase in waste heat after consuming energy or burning fossil fuels is an issue environmentally and economically. Thermoelectric (TE) materials are developed to use in various applications because of their ability ... -
Optimization Placement for SDN Controller: Bell Canada as a Case Study
(University of Waterloo, 2017-11-17)The tremendous proliferation of data traffic has been a key motivator for the upgrading of traditional IP networks One new conceptual model that has been developed for redesigning and managing communication networks is ... -
An Optimization Problem of Internet Routing
(University of Waterloo, 2014-09-23)As the Internet usage grows, existing network infrastructure must deal with increasing demand. One way to deal with this is to increase network capacity, and another, is to set network parameters appropriately. In this ... -
Optimization under Uncertainty for E-retail Distribution: From Suppliers to the Last Mile
(University of Waterloo, 2021-09-03)This thesis examines problems faced in the distribution management of e-retailers, in different stages of the supply chain, while accounting for sources of uncertainty. The first problem studies distribution planning, ...