Browsing Health (Faculty of) by Subject "oxidative stress"
Now showing items 1-2 of 2
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Mechanisms of over-active endothelium-derived contracting factor signaling causing common carotid artery endothelial vasomotor dysfunction in hypertension and aging
(University of Waterloo, 2011-03-09)Background and Purpose: The endothelium is a single-cell layer positioned at the blood-vascular wall interface, where in response to blood-borne signals and hemodynamic forces, endothelial cells act as central regulators ... -
The role of phospholamban (PLN) in potential protection of sarc(endo)plasmic reticulum Ca2+-ATPase (SERCA) against oxidative stress
(University of Waterloo, 2015-01-23)Sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) sequesters Ca2+ from the cytosol to: i) aid in muscular relaxation and ii) refill SR Ca2+ stores for release upon subsequent stimulus for contraction. SERCA function is ...