Browsing Science (Faculty of) by Author "Crouse, Jeff"
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Ligand Specificity and Affinity in the Sulforhodamine B Binding RNA Aptamer
Piccolo, Kyle; McNeil, Brooke; Crouse, Jeff; Lim, Su Ji; Hopkins, W. Scott; Dieckmann, Thorsten (Elsevier Inc., 2020-07-18)Binding affinity and selectivity are critical properties of aptamers that must be optimized for any application. The sulforhodamine B binding RNA aptamer (SRB‐2) is a somewhat promiscuous aptamer that can bind ligands ... -
A parallelized molecular collision cross section package with optimized accuracy and efficiency
Ieritano, Christian; Crouse, Jeff; Campbell, J. Larry; Hopkins, W. Scott (Royal Society of Chemistry, 2019)Ion mobility-based separation prior to mass spectrometry has become an invaluable tool in the structural elucidation of gas-phase ions and in the characterization of complex mixtures. Application of ion mobility to structural ...