Browsing Science (Faculty of) by Type "Doctoral Thesis"
Now showing items 21-40 of 984
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An ALMA View of Molecular Gas in Brightest Cluster Galaxies
(University of Waterloo, 2018-09-25)In this thesis I use ALMA observations to map the distribution and kinematics of molecular gas in the brightest cluster galaxies of three galaxy clusters: 2A0335+096, RXJ0821+0752, and RXCJ1504-0248. The goal is to understand ... -
Alternative splicing of Lymnaea Cav3 and NALCN ion channel genes serves to alter biophysical properties, membrane expression, and ion selectivity
(University of Waterloo, 2012-08-30)Evidence is presented that Lymnaea contains homologues for mammalian Cav3 and NALCN 4-domain ion channels, which retain key amino acid sequence motifs that differentiate these channels from other 4-domain types. Molecular ... -
Ammonia-oxidizing archaea in engineered biofiltration systems
(University of Waterloo, 2016-12-21)Ammonia is a nitrogenous metabolic waste product that is produced by all animal life. High concentrations of ammonia are toxic to animals and may result in algal blooms and eutrophication in aquatic environments. To prevent ... -
Amplitudes in the Spin Foam Approach to Quantum Gravity
(University of Waterloo, 2017-07-31)In this thesis, we study a Spin Foam model for 4D Riemannian quantum gravity, and propose a new way of imposing the simplicity constraints that uses the recently developed holomorphic representation. Rather than imposing ... -
Analysis of heat shock protein 30 gene expression and function in Xenopus laevis A6 kidney epithelial cells
(University of Waterloo, 2014-04-30)Heat shock proteins (HSPs) are molecular chaperones that assist in protein synthesis, folding and degradation and prevent stress-induced protein aggregation. The present study examined the pattern of accumulation of HSP30 ... -
Analysis of plasma chemokines and circulating tumour cells in colorectal and breast cancer patient peripheral blood
(University of Waterloo, 2020-01-22)Circulating tumour cells (CTCs) provide a prognostic value in solid tumours including colorectal and breast. Enumeration of tumour cells from blood is becoming a common practice in informing prognosis and may guide therapy ... -
Antifungal ocular drug delivery via contact lenses using a novel in vitro eye model
(University of Waterloo, 2016-04-21)Purpose: The purpose of this thesis was to evaluate the potential of contact lenses (CLs) as an antifungal drug delivery device, and to develop an in vitro eye model to test thereof. Methods: The first three chapters ... -
Antimicrobial Peptide Daptomycin and its Inhibition by Pulmonary Surfactant: Biophysical Studies using Model Membrane Systems
(University of Waterloo, 2017-04-25)Daptomycin is a lipopeptide antibiotic that is clinically used to treat severe infections caused by Gram-positive bacteria. It is highly potent against resistant strains of bacteria such as methicillin-resistant Staphylococcus ... -
The appearance of hyper-reflective superficial epithelial cells observed using in vivo confocal microscopy
(University of Waterloo, 2010-01-22)Purpose: Hyper-reflective superficial cells were an unexpected finding while examining the corneal epithelium using confocal microscopy (CM), during an MSc thesis conducted in 2006 at the University of Waterloo, Canada. ... -
Application and assessment of multi-wavelength measurements of variable chlorophyll a fluorescence for analysis of irradiance stress, physiological state and community composition in freshwater phytoplankton
(University of Waterloo, 2018-04-24)Phytoplankton are a diverse group of organisms of fundamental importance in aquatic ecosystems. Exposure to high levels of photosynthetically active and ultraviolet radiation (PAR and UVR) is unavoidable for most phytoplankton ... -
Application of Biochar to Stabilize Mercury in Riverbank Sediments and Floodplain Soils from South River, VA under Conditions Relevant to Riverine Environments
(University of Waterloo, 2020-01-07)Disposal of mercury (Hg) containing products related to industrial activities has led to large-scale watershed contamination across the globe, posing long-term risks to human health due to its persistent properties. Hg in ... -
The Application of Digital Filters to Improve Visibility for People with Maculopathy
(University of Waterloo, 2007-09-28)Purpose: Previous studies have shown that some digital filters can enhance picture-image visibility for people with visual impairment. The ultimate purposes of this study are to determine the improvement of picture-image ... -
Application of Solid Phase Microextraction for Lipid Analysis and Lipidomics
(University of Waterloo, 2016-01-29)Although the latest advancements in lipid analysis technology provide an excellent opportunity for the comprehensive study of lipidome, fulfilling the analytical requirements at the desired quality is still a major ... -
Applications of Adiabatic Approximation to One- and Two-electron Phenomena in Strong Laser Fields
(University of Waterloo, 2010-12-20)The adiabatic approximation is a natural approach for the description of phenomena induced by low frequency laser radiation because the ratio of the laser frequency to the characteristic frequency of an atom or a molecule ... -
Applications of Iodonium Ylides for Donor-Acceptor Cyclopropane Synthesis
(University of Waterloo, 2021-11-30)The application of hypervalent iodine (HVI) reagents in the field of organic chemistry has emerged as a viable option for many different useful organic transformations. There have been many considerable contributions made ... -
Applications of the Wormlike Chain Model in Polymer Physics: Self-consistent Field Theory
(University of Waterloo, 2013-04-30)The self-consistent field theory (SCFT) has reveived a great success in prediction of the physical properties of a variety of polymeric systems in the recent two decades. However, the traditional SCFT is based on the ... -
Arborescent Copolymers: Synthesis, Properties & Metallic Nanoparticle Templating
(University of Waterloo, 2011-08-26)Graft copolymers with a dendritic (arborescent) architecture and unimolecular micelle properties have been synthesized and examined for their solution properties as well as their ability to serve as templates for the ... -
Arborescent Core–Shell–Corona Copolymers by Self-Assembly as Templates for the Preparation of Metallic Nanoparticles
(University of Waterloo, 2020-11-19)The preparation of metallic nanoparticles has been a rapidly growing field of research in recent years, because of the unique physical properties and applications of these materials. The development of applications for ... -
Arborescent Polymers From "Click" Chemistry and Other Methods
(University of Waterloo, 2014-01-02)Graft polymers with a dendritic architecture (arborescent polymers) were synthesized by “click”, anionic, and cationic grafting. Arborescent polystyrene and polybutadiene systems were synthesized by “click” coupling using ... -
Arborescent Polypeptides for Sustained Drug Delivery Applications
(University of Waterloo, 2017-08-09)This Ph.D. dissertation describes the synthesis of arborescent copolymers of generations G1 and G2 designed to serve as drug delivery nanocarriers for cancer treatment. Poly(γ-benzyl L-glutamate) (PBG) building blocks were ...