Browsing Science (Faculty of) by Subject "Pyolysin"
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Functional Characterization of Arcanobacterium pyogenes Pyolysin in an Oligomeric Form, and the Binding of CAMP Factor to IgG.
(University of Waterloo, 2007-12-04)The work described in this thesis deals with two pore forming toxins, namely Arcanobacterium pyogenes pyolysin and Streptococcus agalactiae CAMP factor. Pyolysin (PLO) belongs to the homologous group of cholesterol-dependent ... -
Investigations on the Oligomerization of Pyolysin, a Cholesterol-Dependent Cytolysin
(University of Waterloo, 2011-01-25)The bacterial toxin pyolysin (PLO) is a member of the family of Cholesterol-Dependent Cytolysins, which form large, oligomeric pores in cholesterol-containing membranes. The general CDC structure has an elongated shape and ... -
Oligomerization and hemolytic properties of the C-terminal domain of pyolysin, a cholesterol-dependent cytolysin
(NRC Research Press, 2013-04)Pyolysin (PLO) belongs to the homologous family of the cholesterol-dependent cytolysins (CDCs), which bind to cell membranes containing cholesterol to form oligomeric pores of large size. The CDC monomer structure consists ... -
Partial oligomerization of pyolysin induced by a disulfide-tethered mutant
(NRC Research Press, 2012-12)The bacterial toxin pyolysin (PLO) belongs to the family of cholesterol-dependent cytolysins (CDCs), which form large, ring-shaped oligomeric pores in cholesterol-containing membranes. Monomeric CDC molecules have a structure ...