Browsing Biology by Title
Now showing items 332-351 of 600
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Investigating the involvement of FHA domain lateral surfaces in DNA damage and cell cycle checkpoint responses in Saccharomyces cerevisiae
(University of Waterloo, 2023-08-30)Since the discovery of the Forkhead-associated (FHA) domain in 1995, research groups have pursued the characterization of FHA domains and the interactions that they regulate through the lens of their pThr-epitope binding ... -
Investigating the localization and functional significance of adenine phosphoribosyltransferase1 in Arabidopsis chloroplasts
(University of Waterloo, 2014-09-02)Adenine phosphoribosyltransferase (APT) is a housekeeping enzyme that catalyses the principal route of adenine recycling in plants. Of the five APT genes encoded in the Arabidopsis genome, APT1 is the most highly expressed. ... -
Investigating the Outer Envelope Localization of OEP 18 in A. thaliana Chloroplasts
(University of Waterloo, 2021-10-26)Plastids are plant organelles with specialized functions including photosynthesis. The specialized function of each plastid is informed by its distinct and dynamically regulated proteome. The majority of plastid proteins ... -
Investigating the Role of Deoxyhypusine Synthase in the Invasiveness of PC3 Cells Using siRNA
(University of Waterloo, 2008-08-11)Deoxyhypusine synthase (DHS) catalyzes the first step in the hypusination of eukaryotic translation initiation factor 5A (eIF5A). In human cells, two eIF5A isoforms are present, eIF5A-1 and eIF5A-2, and DHS catalyzes the ... -
Investigating the role of the Smoky River watershed on past ice-jam flood regimes at the Peace-Athabasca Delta via analysis of oxbow lake sediment cores
(University of Waterloo, 2022-06-06)The Peace-Athabasca Delta (PAD) in northern Alberta has been a focus of concern for decades due to decline in frequency and magnitude of ice-jam floods that sustain ecologically and culturally significant shallow perched ... -
Investigating the Use of CRISPR/Cas9 for Genetic Screens in Drosophila
(University of Waterloo, 2021-02-24)The CRISPR/Cas9 system has been adapted into a powerful tool for genetic research. The ability to target regions of a genome in a highly specific manner with a reprogrammable guide RNA has been used in a variety of ... -
Investigating the use of enhancer trapping and Cas9-induced rearrangements to characterize cis-regulatory elements in the Drosophila gene hindsight
(University of Waterloo, 2022-08-22)The gene hindsight (hnt) encodes a transcription factor that is essential for all stages of Drosophila development. Expression of hnt has been observed to promote cell specialization and differentiation of several cell ... -
Investigating the use of variable fluorescence methods to detect phytoplankton nutrient deficiency
(University of Waterloo, 2013-04-29)Variable fluorescence of chlorophyll a (Fv/Fm), measured by pulse amplitude modulated (PAM) fluorometers, is an attractive target for phytoplankton-related water quality management. Lowered Fv/Fm is believed to reflect ... -
Investigating trophic ecology and dietary niche overlap among morphs of Lake Trout in Lake Superior
(University of Waterloo, 2017-01-17)Four morphs of Lake Trout (Salvelinus namaycush, Walbaum 1792) have been identified in Lake Superior: leans, siscowets, humpers, and redfins. In this comprehensive study, the trophic ecology of Lake Trout morphs were ... -
An investigation into marine environments in the eastern Canadian Arctic
(University of Waterloo, 2023-10-20)Arctic marine environments are especially vulnerable to climate change, but detailed scientific data for these ecosystems are lacking due to their remote location and the associated logistical challenges of conducting ... -
Investigation of enzymes catalyzing the production of acetaldehyde from pyruvate in hyperthermophiles
(University of Waterloo, 2012-09-26)Extreme thermophiles and hyperthermophiles are microorganisms capable of growing optimally at 65-79°C and 80°C plus, respectively. Many of the enzymes isolated from them are thermostable, which makes them a potential ... -
Investigation of Flavoproteins Involved in the Metabolism of Anaerobic Hyperthermophilic Microorganisms
(University of Waterloo, 2007-09-12)It was estimated that more than one hundred open reading frames in Pyrococcus furiosus and Thermotoga maritima could encode flavoproteins based on the results of motif search and comparison of genomic annotation to the ... -
Investigation of the role of Hindsight in the development of the Drosophila midgut
(University of Waterloo, 2014-02-21)The Drosophila adult midgut is maintained through the division and differentiation of a population of intestinal stem cells (ISCs) (Issigonis and Matunis, 2010). The epithelial cells of the adult midgut are derived from ... -
Investigation of β-xylosidase, α-L-arabinofuranosidase and acetylesterase from Thermotoga hypogea
(University of Waterloo, 2008-09-03)Hemicellulases are key components in the degradation of plant biomass and carbon flow in nature. Thermotoga hypogea is a bacterium that can grow anaerobically at 90°C. It utilizes carbohydrates and peptides as energy and ... -
Investigations into food web structure in the Beaufort Sea
(University of Waterloo, 2017-12-18)The effects of climate change on marine ecosystems are most pronounced in the Arctic, where ice free summers have been predicted to occur by mid-century. Climate-related changes to sea ice phenology, oceanographic habitat ... -
Investigations into the toxicity and toxicokinetics of individual and binary mixtures of CCME petroleum hydrocarbon distillates in soil
(University of Waterloo, 2012-05-18)The Canada-wide Standards for Petroleum Hydrocarbons (PHC CWS) in soils are remedial standards based on four petroleum distillates (Fraction 1 [F1; ECN C6-C10], Fraction 2 [F2; ECN >C10-C16], Fraction 3 [F3; ECN >C16-C34], ... -
Investigations on the action mode of Bacillus thuringiensis Cyt2Aa1 toxin
(University of Waterloo, 2015-08-11)B. thuringiensis is a Gram-positive bacterium that, while quite otherwise closely related to the soil saprophyte Bacillus cereus, is unique in producing a large variety of membrane-damaging, insecticidal protein toxins. ... -
Island biogeography theory and the urban landscape: stopover site selection by the silver-haired bat (Lasionycteris noctivagans)
(Canadian Science Publishing, 2022-04)Many migratory bats require forested sites for roosting and foraging along their migration path, but increased urbanization and intensive agricultural practices may reduce the availability of stopover sites. Urban forests ... -
Isolation and characterization of bacterial phosphorous metabolism genes from complex microbial communities
(University of Waterloo, 2009-10-05)Phosphorous (P) is an essential nutrient, playing a central role in the life of a bacterial cell. It is involved in cellular metabolic pathways, cell signaling and is a component of many of the cell’s macromolecules. Since ... -
Isotopic niche use by the invasive mysid Hemimysis anomala in the Laurentian Great Lakes basin
(University of Waterloo, 2013-05-03)Invasive species are a known stressor on aquatic ecosystems, particularly in the waters of the Great Lakes basin. A recent invader, Hemimysis anomala, has had significant impacts on the food webs of Europe, where it invaded ...