Browsing Biology by Title
Now showing items 406-425 of 600
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Molecular Mechanism of Starch Digestion by Family 31 Glycoside Hydrolases: Structural Characterization and Inhibition Studies of C-terminal Maltase Glycoamylase and Sucrase Isomaltase
(University of Waterloo, 2014-04-22)Although carbohydrates are a principal component of the human diet, the mechanism of the final stages of starch digestion is not fully understood. One approach to treating metabolic diseases such as type II diabetes, ... -
Molecular methods for evaluating the human microbiome
(University of Waterloo, 2014-01-28)In human microbiome analysis, sequencing of bacterial 16S rRNA genes has revealed a role for the gut microbiota in maintaining health and contributing to various pathologies. Novel community analysis techniques must be ... -
Molecular Phylogeography and Species Discrimination of Freshwater <em>Cladophora</em> (Cladophorales, Chlorophyta) in North America
(University of Waterloo, 2006)<em>Cladophora</em> is a widespread freshwater filamentous cholorophyte genus and is frequently observed in eutrophic waters where it can produce large nuisance blooms. These blooms can have direct impacts on water ... -
Monitoring Wetland Integrity and Restoration Success with Avifauna in the Prairie Pothole Region of Alberta, Canada
(University of Waterloo, 2017-01-19)In response to high wetland losses, and in recognition of the ecological functions and services provided by wetland ecosystems, updated wetland policy in Alberta focuses on protecting these important system and mitigating ... -
Morphological and molecular determination of Fucus (Fucales, Heterokontophyta) biogeography across North American shores
(University of Waterloo, 2009-04-21)The genus Fucus (Phaeophyceae) has nine commonly accepted species, six of which inhabit North American shores: F. gardneri, F. serratus, F. distichus, F. evanescens, F. vesiculosus, and F. spiralis. Fucus inhabit the ... -
Motivational State Influences the Content of Hippocampal Sequences
(University of Waterloo, 2015-08-18)Hippocampal sharp wave-ripple (SWR) associated sequence activity, commonly referred to as replay, has generally been thought of as mediating the transfer of recent experience into the neocortex. However, a number of ... -
Movement of mature and early life stages of the Grand River walleye (Sander vitreus) population in Lake Erie's eastern basin
(University of Waterloo, 2020-09-04)Lake Erie’s commercial and recreational walleye fishery is the largest of the Great Lakes, requiring effective management to maintain a sustainable and complex fishery. Lake Erie’s walleye fishery is composed of multiple ... -
Multi-stressor impacts on fish energetics and stress response: a comparison between lab and field studies
(University of Waterloo, 2017-08-24)Aquatic organisms are continuously exposed to multiple environmental stressors that work cumulatively and synergistically to alter ecosystems. The objective of this study was to investigate the impacts of multiple stressors ... -
Multi-trophic effects of invasive species suppression in a coastal wetland
(University of Waterloo, 2021-05-25)Wetlands provide essential habitat for hundreds of species, including many that are of conservation concern in Canada. In southern Ontario, two wetland complexes, Long Point Peninsula and Rondeau Provincial Park, represent ... -
Multiple Stressors in the Environment: The Effects of Exposure to an Antidepressant (Venlafaxine) and Increased Temperature on Zebrafish Metabolism
(Multidisciplinary Digital Publishing Institute, 2019-11-19)Aquatic organisms are continuously exposed to multiple environmental stressors working cumulatively to alter ecosystems. Wastewater-dominated environments are often riddled by a myriad of stressors, such as chemical and ... -
Multiplex RT-qPCR assay (N200) to detect and estimate prevalence of multiple SARS-CoV-2 Variants of Concern in wastewater
(medRxiv, 2022-04-13)Wastewater-based surveillance (WBS) has become an effective tool around the globe for indirect monitoring of COVID-19 in communities. Quantities of viral fragments of SARS-CoV-2 in wastewater are related to numbers of ... -
Multiscale models of kidney function and diseases
(Elsevier, 2019-09)The kidney is a complex system whose function is the result of synergistic operations among a number of biological processes. The spatial and functional scales of those processes span a wide range. To interrogate kidney ... -
Nanoscale Characterization of Melatonin and Amyloid Beta in Model Membranes- in Relation to Alzheimer's Disease
(University of Waterloo, 2014-12-03)Increasing evidence suggests that cell membranes play an important role in the pathophysiology of Alzheimer's disease (AD). Direct interaction of small molecules, such as cholesterol and melatonin, with cellular membrane ... -
Native Wetland Plant Recovery Following Phragmites australis Invasion
(University of Waterloo, 2022-05-20)Invasive common reed (Phragmites australis ssp. australis) has negatively affected 25% of all Species at Risk in Ontario since its arrival in the twentieth century. This is of particular concern at Long Point and Rondeau, ... -
Near real-time determination of B.1.1.7 in proportion to total SARS-CoV-2 viral load in wastewater using an allele-specific primer extension PCR strategy
(Elsevier, 2021-10-15)"The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome corona- virus 2 (SARS-CoV-2) has claimed millions of lives to date. Antigenic drift has resulted in viral variants ... -
Network centrality analysis of eye-gaze data in autism spectrum disorder
(Elsevier, 2019-08)Individuals suffering from autism spectrum disorder (ASD) exhibit impaired social communication, the manifestations of which include abnormal eye contact and gaze. In this study, we first seek to characterize the spatial ... -
Neural Tube Defect-causing Teratogens Affect Tissue Mechanical Properties and Cytoskeletal Morphology in Axolotl Embryos
(University of Waterloo, 2007-11-22)The teratogenic drugs cytochalasin B and valproic acid have been shown to alter F-actin polymerization, an effect that is crucial in forming microfilaments. Microfilaments form important cytoskeletal structures that maintain ... -
Neuregulin’s role in regulating the anti-inflammatory pathway
(University of Waterloo, 2009-08-12)Inflammation can be up-regulated by microglia and macrophages through the release of pro-inflammatory cytokines such as tumour necrosis factor-alpha (TNF-α). Excess production of TNF-α can lead to a variety of diseases and ... -
A new angle on plastic debris in the aquatic environment: Investigating interactions between viral hemorrhagic septicemia virus (VHSV) and inanimate surfaces
(University of Waterloo, 2009-08-28)Methods of studying the interaction between fish viruses with inanimate surfaces were developed and used to explore several variables. Viral hemorrhagic septicemia virus (VHSV) was used as the model virus. The EPC cell ... -
Non-specific immune response and disease-resistance in Chinook salmon (Oncorhynchus tshawytscha) supplemented with probiotics
(University of Waterloo, 2023-09-21)Finfish aquaculture is the fastest-growing food-production sector in the world. Nevertheless, intensive production faces increased disease outbreaks due to high stock densities and environmental effects. Currently, infectious ...