Browsing Biology by Issue Date
Now showing items 21-40 of 599
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Functional Characterization of Rainbow Trout (<em>Oncorhynchus mykiss</em>) Chemokine 2 (CK-2)
(University of Waterloo, 2006)Chemokines are cytokines with chemoattractant ability, and comprise one of the major groups of molecules in immune system. These are small, secreted proteins cause the migration of leukocytes to the sites of injury. ... -
Chemical Composition of Soybean Root Epidermal Cell Walls
(University of Waterloo, 2006)The root epidermis, being the outermost cell layer of the organ, is in contact with the soil environment. The position of the epidermis determines its important roles, such as taking up water and ions from the surrounding ... -
Using Chemical Crosslinking and Mass Spectrometry for Protein Model Validation and Fold Recognition
(University of Waterloo, 2006)The 3D structures of proteins may provide important clues to their functions and roles in complex biological pathways. Traditional methods such as X-ray crystallography and NMR are not feasible for all proteins, while ... -
A study of innate antiviral mechanisms using fish cell lines
(University of Waterloo, 2006)Understanding basic antiviral mechanisms in vertebrates is essential for developing methods to enhance antiviral responses and promote human and animal health. In fish these antiviral mechanisms are poorly understood, ... -
An Assessment of Hydro-ecological Changes at Two Closed-drainage Basins in the Peace-Athabasca Delta, Alberta, Canada
(University of Waterloo, 2006)Diatom analyses were carried out on sediment cores collected from two low-lying, closed-drainage basins (PAD 9 - 58º46. 46?N, 111º19. 48?W; PAD 12 - 58º57. 29?, 111º19. 74?) in the Peace sector of the Peace-Athabasca ... -
Characterization of the expression and function of <em>Rana catesbeiana</em> HSP30 and <em>Xenopus laevis</em> HSP27
(University of Waterloo, 2006)Exposure of cells to environmental or chemical stressors will initiate the heat shock response, which is mediated by heat shock proteins. Heat shock proteins are molecular chaperones which are classified by size into six ... -
Characterization of Genes involved In Development and Senescence
(University of Waterloo, 2006)Plant development is complex and highly regulated. Tens of thousands of genes have been sequenced for the model plant <em>Arabidopsis thaliana</em>, yet few have been functionally annotated and characterized. This ... -
Characterization of Eukaryotic Translation Initiation Factor 5A isoforms (eIF-5A1 & eIF-5A2) using human cell lines as a model system
(University of Waterloo, 2006)Eukaryotic translation initiation factor 5A (eIF-5A) is the only known cellular protein that contains the post-translationally derived amino acid, hypusine. Initially, eIF-5A was named as a translation initiation factor ... -
Characterization of the role of Orc6 in the cell cycle of the budding yeast <em>Saccharomyces cerevisiae</em>
(University of Waterloo, 2006)The heterohexameric origin recognition complex (ORC) acts as a scaffold for the G1 phase assembly of pre-replicative complexes. Only the Orc1-5 subunits are required for origin binding in budding yeast, yet Orc6 is an ... -
Characterization and expression patterns of five Winter Rye β-1,3-endoglucanases and their role in cold acclimation
(University of Waterloo, 2007-01-23)Winter rye produces ice-modifying antifreeze proteins upon cold treatment. Two of these antifreeze proteins are members of the large, highly conserved, β-1,3-endoglucanase family. This project was designed to identify ... -
Determining the subcellular localization of adenosine kinase and SAH hydrolase and their roles in adenosine metabolism
(University of Waterloo, 2007-01-23)Housekeeping enzymes are vital to the metabolism of all plant cells. Two such enzymes adenosine kinase (ADK) and S-adenosylhomocysteine (SAH) hydrolase share a similar function: both sustain S-adenosylmethionine-dependent ... -
Using Tetrahymena thermophila to study the role of protozoa in the inactivation of viruses in water
(University of Waterloo, 2007-04-24)Ciliated protozoa, such as Tetrahymena thermophila, are ubiquitous in the aquatic environment, including in sewage treatment plants. Their ability to graze on particulates could influence water quality in a number of ways, ... -
Hepatic Steatosis and TNF-α Signaling
(University of Waterloo, 2007-04-24)The overall objective of this research was to investigate the status of tumor necrosis factor-α (TNF-α), and molecules associated with its signaling, in the pathological state of hepatic steatosis. The effect of NSAID ... -
Occurrence and Seasonal Variability of Selected Pharmaceuticals in Southern Ontario Drinking Water Supplies
(University of Waterloo, 2007-04-27)The presence and seasonal variability of human and veterinary pharmaceuticals in surface water (raw water) and treated water samples from two drinking water facilities in Southern Ontario was investigated. Water samples ... -
1-AMINOCYCLOPROPANE-1-CARBOXYLATE (ACC) DEAMINASE GENES IN RHIZOBIA: ISOLATION AND CHARACTERIZATION
(University of Waterloo, 2007-05-14)A collection of 233 putative Rhizobia strains from 30 different sites across Saskatchewan, Canada was assayed for ACC deaminase activity, with 27 of the strains displaying activity. When all 27 strains were characterized ... -
Regulation of MH Class II Associated Invariant Chain in Oncorhynchus mykiss
(University of Waterloo, 2007-05-22)Major histocompatibility complex (MHC) class II associated invariant chain is a chaperone of the mammalian MHC class II antigen presentation pathway. It is responsible for targeting the MHC class II dimer to the endocytic ... -
Examining oil sands dissolved carbon and microbial degradation using stable isotope analysis
(University of Waterloo, 2007-05-22)Oil sands mining operations in northeastern Alberta are rapidly expanding. Upgrading and extracting the bitumen from the sand requires large volumes of water generating large quantities of oil sands process water/materials ... -
Onion Root Anatomy and the Uptake of Sulphate and Phosphate Ions
(University of Waterloo, 2007-06-12)Ions in the soil solution traverse many layers (epidermis, exodermis, central cortex, and endodermis) within the root to reach the stele. The endodermis is present in almost all vascular plants while the exodermis is found ... -
Impact of non-steroidal anti-inflammatory drugs on the adaptive responses to stress in rainbow trout
(University of Waterloo, 2007-06-19)Pharmaceutical drugs are used extensively by humans and domestic animals. The detection of compounds such as non-steroidal anti-inflammatory drugs (NSAIDs) in effluents of sewage treatment plants and surface waters has ... -
Development and application of plant macrofossils for paleolimnological reconstructions in the Slave River Delta, N.W.T.
(University of Waterloo, 2007-08-29)This thesis combines detailed analyses of living plant communities with paleolimnological methods to develop the use of plant macrofossils as an effective tool to track hydroecological changes in ponds of the Slave River ...