Browsing Optometry and Vision Science by Title
Now showing items 87-106 of 249
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The Effects of 1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride (ML-7) on the Lens During Avian Accommodation In Situ
(University of Waterloo, 2009-12-17)A previous study in chickens revealed that myosin light chain kinase (MLCK), f actin, and myosin are found on the crystalline lens. Their polygonal arrangement at the posterior surface resembles a muscle tissue, which ... -
Effects of ML-7 on the Actomyosin Networks of the Avian Crystalline Lens
(University of Waterloo, 2022-04-29)Assemblies of contractile proteins such as actin, myosin and myosin light chain kinase (MLCK) are found on the posterior surface of the lens fibre cells. The mechanical properties of chicken lenses, as well as their focal ... -
The Effects of tDCS Across the Spatial Frequencies and Orientations that Comprise the Contrast Sensitivity Function
(Frontiers Media, 2015-11-27)Transcranial Direct Current Stimulation (tDCS) has recently been employed in traditional psychophysical paradigms in an effort to measure direct manipulations on spatial frequency channel operations in the early visual ... -
Effects of Temperature on the Proliferation of Human and Fish Lens Epithelial Cells
(University of Waterloo, 2019-08-29)Crystallins are proteins that confer refractive properties to the crystalline lens. All vertebrate lenses contain α- and β-crystallins, and often a third major crystallin. Crystallins can have additional non-refractive ... -
Electrophysiological measures of optic nerve function
(University of Waterloo, 2021-08-26)The contribution of retinal ganglion cells (RGCs) to human electroretinograms (ERGs) is known, but that of chicken (Gallus gallus domesticus) is not clear. This project seeks to determine the effect of RGC dysfunction on ... -
Estimation of Heading direction Using Optic Flow
(University of Waterloo, 2019-08-26)Background The purpose of this study was to investigate the effect of the reduction of the uniocular light luminance as well as the effect of unequal retinal image sizes by using uniocular size lenses, on the heading ... -
Evaluation of a Novel Glycoprotein on Commercial Contact Lenses
(University of Waterloo, 2015-05-22)PURPOSE The purpose of this thesis was to evaluate the interaction of a novel glycoprotein, known as proteoglycan 4 (PRG4), with various commercial contact lenses. METHODS PRG4 was investigated for its effects on ... -
The evaluation of bulbar redness grading scales
(University of Waterloo, 2010-01-12)The use of grading scales is common in clinical practice and research settings. A number of grading scales are available to the practitioner, however, despite their frequent use, they are only poorly understood and may be ... -
Examination of Contact Lenses and Dry Eye Using Evaporimetry
(University of Waterloo, 2022-01-14)Purpose: Evaporimetry is a non-invasive technique used to assess the stability of the tear film. The test measures the rate of tear evaporation, and has been used to investigate dry eye, contact lenses, and the efficacy ... -
Exercise-Induced Fatigue and Caffeine Supplementation Affect Psychomotor Performance but Not Covert Visuo-Spatial Attention
(Public Library of Science, 2016-10-21)Fatigue resulting from strenuous exercise can impair cognition and oculomotor control. These impairments can be prevented by administering psychostimulants such as caffeine. This study used two experiments to explore the ... -
Explainable AI for retinal OCT diagnosis
(University of Waterloo, 2021-01-20)Artificial intelligence methods such as deep learning are leading to great progress in complex tasks that are usually associated with human intelligence and experience. Deep learning models have matched if not bettered ... -
Exploration of the Underlying Visual Perceptual and Cognitive Mechanisms of Dynamic Visual Acuity
(University of Waterloo, 2024-01-25)Purpose: Dynamic visual acuity (dynamic VA) is a complex, perceptual ability of the visual system that involves determining fine details of objects as they move across one’s field of view (1–4). Over the years, there has ... -
Extended Latanoprost Release from Commercial Contact Lenses: In Vitro Studies Using Corneal Models
(Public Library of Science, 2014-10-09)In this study, we compared, for the first time, the release of a 432 kDa prostaglandin analogue drug, Latanoprost, from commercially available contact lenses using in vitro models with corneal epithelial cells. Conventional ... -
Fabrication of an enzyme responsive biomaterial for the treatment of recurrent corneal erosion
(University of Waterloo, 2023-04-11)Purpose: Recurrent corneal erosion (RCE) arising from the loss of superficial corneal epithelial cells causes tremendous ocular pain affecting one’s productivity and quality of life. RCE was traditionally treated with eye ... -
Fabrication of microfluidic chip using 3D printing for ocular cell studies
(University of Waterloo, 2023-09-25)Purpose: This thesis aimed to create a polydimethylsiloxane (PDMS) microfluidic chip utilizing low-cost commercial 3D printers and to integrate human corneal epithelial cells (HCEC) into the fabricated chip. Methods: The ... -
Fatigue related impairments in oculomotor control are prevented by caffeine
(Nature, 2016-05-25)Strenuous exercise can result in an inability of the central nervous system to drive skeletal muscle effectively, a phenomenon known as central fatigue. The impact of central fatigue on the oculomotor system is currently ... -
Fine Motor Skills of Children With Amblyopia Improve Following Binocular Treatment
(Association for Research in Vision and Ophthalmology, 2016-09-08)Purpose: The purpose of this study was to determine whether reduced fine motor skills in children with amblyopia improve after binocular treatment and whether improvements are sustained once treatment has ceased. Methods: ... -
Fish (Oreochromis niloticus) as a Model of Refractive Error Development
(University of Waterloo, 2009-01-13)Myopia is a common ocular condition worldwide and the mechanism of myopia is still not clear. A number of animal models of myopia and refractive error development have been proposed. The fact that form deprivation myopia ... -
Fixational eye movements in strabismic amblyopia
(University of Waterloo, 2013-04-29)Purpose: To test the hypothesis that the fixational stability (FS) of the amblyopic eye (AME) in strabismics will improve when binocular integration is enhanced through ocular alignment and inter-ocular suppression is ... -
Fluoxetine Does Not Enhance Visual Perceptual Learning and Triazolam Specifically Impairs Learning Transfer
(Frontiers Media, 2016-10-19)The selective serotonin reuptake inhibitor fluoxetine significantly enhances adult visual cortex plasticity within the rat. This effect is related to decreased gamma-aminobutyric acid (GABA) mediated inhibition and identifies ...